Psychological Capital and Quality of Life Among Cancer Survivors: The Mediating Role of Post-Traumatic Growth and the Moderating Role of Fear of Recurrence
Keywords:
Psychological capital, quality of life, cancer survivors, post-traumatic growth, fear of cancer recurrence, moderated mediationAbstract
Objective: This study aimed to examine the relationship between psychological capital and quality of life among cancer survivors in Brazil, with post-traumatic growth as a mediating variable and fear of cancer recurrence as a moderating variable.
Methods and Materials: This descriptive-correlational cross-sectional study was conducted among 384 adult cancer survivors in Brazil who had completed the main phase of cancer treatment and were receiving follow-up or survivorship care. Participants completed standardized self-report measures assessing psychological capital, post-traumatic growth, fear of cancer recurrence, and quality of life. Data were analyzed using SPSS and AMOS. Pearson correlation coefficients were used to examine relationships among the main variables. Mediation was tested through bootstrapping with 5,000 resamples, and moderation and moderated mediation effects were examined using interaction terms and conditional effect analysis. Model fit was evaluated using χ², CFI, TLI, RMSEA, and SRMR indices.
Findings: Psychological capital was significantly and positively associated with post-traumatic growth (β = 0.45, p < 0.001) and quality of life (β = 0.36, p < 0.001). Post-traumatic growth also had a significant positive effect on quality of life (β = 0.20, p < 0.001). The indirect effect of psychological capital on quality of life through post-traumatic growth was significant (B = 0.10, 95% CI [0.05, 0.16]), indicating partial mediation. Fear of cancer recurrence had a significant negative effect on quality of life (β = -0.42, p < 0.001) and significantly moderated the direct path between psychological capital and quality of life (β = -0.16, p = 0.001) and the path between post-traumatic growth and quality of life (β = -0.12, p = 0.009). The index of moderated mediation was significant (B = -0.002, 95% CI [-0.004, -0.001]).
Conclusion: Psychological capital was associated with better quality of life among cancer survivors both directly and indirectly through post-traumatic growth, while fear of recurrence weakened these positive pathways. These findings highlight the importance of integrating positive psychological resource enhancement with fear-of-recurrence management in survivorship care.
Downloads
References
Bolliger, C. T., Way, K., Michel, G., Sodergren, S. C., & Darlington, A. S. (2024). Mapping and Comparing the Quality of Life Outcomes in Childhood and Adolescent and Young Adult Cancer Survivors: An Umbrella Review and Future Directions. Quality of Life Research, 34(3), 633-656. https://doi.org/10.1007/s11136-024-03825-7
Chen, L., Ren, T., Tan, Y., & Li, H. (2022). Global Trends of Research on Depression in Breast Cancer: A Bibliometric Study Based on VOSviewer. Frontiers in psychology, 13. https://doi.org/10.3389/fpsyg.2022.969679
Cho, H., Kang, D., Shin, D. W., Kim, N., Lee, S. K., Lee, J. E., Nam, S. J., & Cho, J. (2024). Social Support During Re-Entry Period and Long-Term Quality of Life in Breast Cancer Survivors: A 10-Year Longitudinal Cohort Study. Quality of Life Research, 33(5), 1287-1295. https://doi.org/10.1007/s11136-024-03599-y
Drury, A., Payne, S., & Brady, A. M. (2021). Prevalence vs Impact: A Mixed Methods Study of Survivorship Issues in Colorectal Cancer. Quality of Life Research, 31(4), 1117-1134. https://doi.org/10.1007/s11136-021-02975-2
Duran, S., Varol, U., Tekir, Ö., & Soytürk, A. H. (2024). Resilience’s Impact on Quality of Life and Post-Traumatic Growth in Breast Cancer Patients During Treatment. Breast Cancer, 31(5), 807-814. https://doi.org/10.1007/s12282-024-01594-2
Ellis, K. R., Koechlin, H., Gerido, L. H., Hecht, H. K., Jones, C., Raji, D., Northouse, L., & Katapodi, M. C. (2024). Predictors and Interdependence of Quality of Life in a Random Sample of Long‐Term Young Breast Cancer Survivors and Their Biological Relatives. Cancer Medicine, 13(20). https://doi.org/10.1002/cam4.70328
Evans, C., Saliba‐Serre, B., Préau, M., Bendiane, M. K., Gonçalvès, A., Signoli, M., & Bouhnik, A. D. (2022). Post Traumatic Development Five Years After Cancer: Identification of Associated Actionable Factors. https://doi.org/10.21203/rs.3.rs-1303886/v1
Gallego, A., Beato, C., Brozos, E., Cruz, S. d. l., & García, R. V. (2024). Spanish Society of Medical Oncology Recommendations for Comprehensive Assessment and Care of Cancer Survivors’ Needs. Clinical & Translational Oncology, 27(1), 95-107. https://doi.org/10.1007/s12094-024-03571-9
Janitra, F. E., Aini, N., & Wicaksana, A. L. (2023). Resilience-Related Breast Cancer: A Concept Analysis. Nurse Media Journal of Nursing, 13(1), 31-55. https://doi.org/10.14710/nmjn.v13i1.45996
Janssen, S. H. M., Winette, T. A. v. d. G., Daniël, J. v. d. M., Manten‐Horst, E., & Husson, O. (2021). Adolescent and Young Adult (AYA) Cancer Survivorship Practices: An Overview. Cancers, 13(19), 4847. https://doi.org/10.3390/cancers13194847
Jin, D.-L., Choi, W. J., Hur, R., Seo, H. J., & Yoon, S. J. (2023). Cancer Survivorship Programs and Care Delivery Models for Cancer Survivors’ Transition in South Korea: A Scoping Review. https://doi.org/10.21203/rs.3.rs-3209058/v1
Li, L., Song, Y., Jin, S., Wang, H., Wang, L., Zhu, X., Song, C., Zhang, X., & Zhuang, S. (2025). Exploring the Influence of Rumination and Perceived Social Support on Post-Traumatic Growth in Postoperative Gastric Cancer Patients: A Network Analysis. https://doi.org/10.21203/rs.3.rs-7356250/v1
Lim, C. Y. S., Laidsaar‐Powell, R., Young, J., Kao, S. C., Zhang, Y., & Butow, P. (2021). Colorectal Cancer Survivorship: A Systematic Review and Thematic Synthesis of Qualitative Research. European Journal of Cancer Care, 30(4). https://doi.org/10.1111/ecc.13421
Lim, J. w., Zhang, A., & Zebrack, B. (2023). Technology-Based Cancer Survivorship Care Interventions: A Systematic Review and Meta-Analysis. Research on Social Work Practice, 34(7), 757-780. https://doi.org/10.1177/10497315231199940
Lin, C. C., & Her, Y. N. (2023). Demoralization in Cancer Survivors: An Updated Systematic Review and Meta‐analysis for Quantitative Studies. Psychogeriatrics, 24(1), 35-45. https://doi.org/10.1111/psyg.13037
López, V., & Klainin‐Yobas, P. (2021). Health Promotion Among Cancer Patients: Innovative Interventions. 227-244. https://doi.org/10.1007/978-3-030-63135-2_17
Martens, K., Ulrich, G. R., Ranby, K. W., & Kilbourn, K. (2021). What Matters Most? Predictors of Quality of Life and Life Satisfaction Among Young Breast Cancer Survivors. Cancer Nursing, 44(6), E727-E734. https://doi.org/10.1097/ncc.0000000000000967
McErlean, G., Tapp, C., Brice, L., Gilroy, N., Kabir, M., Greenwood, M., Larsen, S., Moore, J. J., Gottlieb, D., Hertzberg, M., Brown, L., Hogg, M., Huang, G., Wård, C., & Kerridge, I. (2023). Predictors of Post Traumatic Growth in Allogeneic Hematopoietic Stem Cell Transplantation Survivors: A Cross-Sectional Survey. BMC psychology, 11(1). https://doi.org/10.1186/s40359-023-01204-4
Menger, F., Deane, J., Patterson, J., Fisher, P., O’Hara, J., & Sharp, L. (2022). The Nature and Content of Rumination for Head and Neck Cancer Survivors. Frontiers in psychology, 13. https://doi.org/10.3389/fpsyg.2022.995187
Menger, F., Deane, J., Patterson, J., Fisher, P., O’Hara, J., & Sharp, L. (2025). “After the Horrible Cancer…” Post-Traumatic Growth Through the Lens of Head and Neck Cancer Survivors. Journal of Psychosocial Oncology Research and Practice, 7(1). https://doi.org/10.1097/or9.0000000000000158
Meoded, M. D., Mehedințu, C., & Cirimbei, C. (2025). Psycho-Oncology in Breast Cancer: Supporting Women Through Distress, Treatment, and Recovery—Three Arguments—Rapid Narrative Review. Medicina, 61(6), 1008. https://doi.org/10.3390/medicina61061008
Nam, S. H., & Kim, J. (2025). Overcoming Fear of Cancer Recurrence in Young Adult Survivors: A Resource-Based Approach Centred on Healthcare Professionals – A Protocol for Systematic Reviews and Thematic Synthesis. BMJ open, 15(8), e105263. https://doi.org/10.1136/bmjopen-2025-105263
Neris, R. R., Papathanassoglou, E., Ana Carolina Andrade Biaggi, L., García‐Vivar, C., & Nascimento, L. C. (2024). Quality of Life of Adolescents and Young Adult Survivors of Childhood Cancer: A Qualitative Study. Journal of Advanced Nursing, 81(7), 4110-4121. https://doi.org/10.1111/jan.16608
Ogunsanya, M. E., Saintibert, J., Bolajoko, O., Hooks, D., Clifton, S., & Odedina, F. T. (2025). Mapping Behavioral Research in Post‐Treatment Cancer Care in Sub‐Saharan Africa: A Scoping Review. Psycho-Oncology, 34(3). https://doi.org/10.1002/pon.70106
Paunescu, A.-C., Kvaskoff, M., Delpierre, C., Delrieu, L., Jacob, G., Pannard, M., & Préau, M. (2025). The Influence of Locus of Control, Coping Strategies and Time Perspective on Post-Traumatic Growth in Survivors With Primary Breast Cancer. BMC psychology, 13(1). https://doi.org/10.1186/s40359-025-02353-4
Pawłowski, P. (2025). The Cost of Victory Over Cancer: Psychosocial Dysfunction and Depressive Symptoms Among Polish Adolescent Cancer Survivors in the Context of Quality of Life and Psychosocial Health. Cancers, 17(24), 3916. https://doi.org/10.3390/cancers17243916
Ruiz-Romeo, M., Ciria‐Suarez, L., Arizu-Onassis, A., Medina, J. C., Serra-Blasco, M., Souto-Sampera, A., Flix-Valle, A., Lucía del Carmen González, A., Villanueva‐Bueno, C., Escudero-Vilaplana, V., Linares, E. J., & Ochoa, C. (2026). Integrating Online Peer Support Into Psychosocial Care for Breast Cancer Survivorship: Effects on Anxiety and Post-Traumatic Growth. https://doi.org/10.21203/rs.3.rs-9616428/v1
Sajid, U., Batool, S. F., Ahmed, S., Karatela, N., Qaisar, H., & Noushad, S. (2022). Psychophysiological Well-Being &Amp; Quality of Life (QoL) Among Breast Cancer Patients After Mastectomy. International Journal of Endorsing Health Science Research (Ijehsr), 10(4), 446-454. https://doi.org/10.29052/ijehsr.v10.i4.2022.446-454
Su, Y., Zhang, S., Duan, L., & Hu, X. (2026). The Effectiveness of Telemedicine‐Based Psychosocial Intervention for Fear of Cancer Recurrence, Mindfulness, and Posttraumatic Growth in Cancer Survivors: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials. Psycho-Oncology, 35(1). https://doi.org/10.1002/pon.70377
Tock, W. L., Maheu, C., Blondin, S., Lee, V., Neuman, S., & Meterissian, S. (2025). The Effect of Life Coaching on Post‐Traumatic Growth and Well‐Being in Breast Cancer Survivors: A Randomized Controlled Trial. Psycho-Oncology, 34(10). https://doi.org/10.1002/pon.70295
Wang, Z., Chen, X., Zhou, J., Loke, A. Y., & Li, Q. (2023). Posttraumatic Growth in Colorectal Cancer Survivors: A Systematic Review. Clinical Psychology & Psychotherapy, 30(4), 740-753. https://doi.org/10.1002/cpp.2838
Wenji, X. U., Sun, J., Y, L., Chen, Y. C., 智晓旭, Zhang, L., & Du, S. (2026). Posttraumatic Growth Among Cancer Patients: A Conceptual Analysis. Nursing and Health Sciences, 28(2). https://doi.org/10.1111/nhs.70371
Yeoh, S. A., Bowie, A., Tim, W., Russell, H., & Beatty, L. (2026). Effectiveness of Positive Psychology Interventions for Cancer Survivors: A Systematic Review and Meta‐Analysis. Cancer Medicine, 15(1). https://doi.org/10.1002/cam4.71368
Downloads
Published
Submitted
Revised
Accepted
Issue
Section
License
Copyright (c) 2026 Yanelis Batista (Author); Thiago Moreira

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.