Effectiveness of a Mentalization-Based Relationship Enrichment Package Compared to Emotionally Focused Couple Therapy on Anxiety Sensitivity, Intolerance of Uncertainty, and Anger Control in Infertile Couples
Keywords:
Mentalization-Based Relationship Enrichment, Emotion-Focused Couple Therapy, Anxiety Sensitivity, Intolerance of Uncertainty, Anger Control, Infertile CouplesAbstract
Objective: This study aimed to develop a Mentalization-Based Relationship Enrichment (MBRE) package and compare its effectiveness with Emotionally Focused Couple Therapy (EFCT) on anxiety sensitivity, intolerance of uncertainty, and anger control among infertile couples.
Methods and Materials: This research employed a sequential exploratory mixed-methods design. In the qualitative phase, semi-structured interviews with infertile couples and experts, along with thematic analysis, were used to develop the MBRE package. Content validity was confirmed using CVR and CVI indices. In the quantitative phase, a quasi-experimental pretest–posttest design with a control group and three-month follow-up was conducted. Thirty-six infertile couples were selected purposively and randomly assigned to an MBRE group, an EFCT group, or a control group. Data were collected using the Anxiety Sensitivity Index (ASI), Intolerance of Uncertainty Scale (IUS), and Novaco Anger Scale, and analyzed using repeated-measures ANOVA and Bonferroni post hoc tests.
Findings: Repeated-measures ANOVA showed significant group × time interaction effects for all three variables (p < .001), indicating differential changes over time across conditions. Both MBRE and EFCT produced significant reductions in anxiety sensitivity and significant improvements in intolerance of uncertainty and anger control compared to the control group (p < .001). Bonferroni comparisons revealed that EFCT had a stronger effect than MBRE on reducing anxiety sensitivity at posttest and follow-up (p < .001). Both interventions maintained their beneficial effects at the three-month follow-up, demonstrating treatment stability over time (p < .001).
Conclusion: Both MBRE and EFCT effectively reduced anxiety sensitivity and improved intolerance of uncertainty and anger control in infertile couples, with EFCT showing greater impact on anxiety sensitivity. The newly developed MBRE package presents a promising relational and emotional intervention for couples experiencing infertility-related distress.
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References
Akintayo, A. A., Aduloju, O. P., Dada, M. U., Abiodun-Ojo, O. A., Oluwole, L. O., & Ade-Ojo, I. P. (2022). Comparison of self-esteem and depression among fertile and infertile women in a low resource setting. Journal of Obstetrics and Gynaecology, 42(5), 1198-1203. https://doi.org/10.1080/01443615.2021.1945002
Allan, N. P., Gorka, S. M., Saulnier, K. G., & Bryan, C. J. (2023). Anxiety sensitivity and intolerance of uncertainty: transdiagnostic risk factors for anxiety as targets to reduce risk of suicide. Current psychiatry reports, 25(4), 139-147. https://doi.org/10.1007/s11920-023-01413-z
Antequera-Jurado, R., Moreno-Rosset, C., & Ramírez-Uclés, I. (2023). The specific psychosocial modulator factors of emotional adjustment in infertile individuals compared to fertile people. Current Psychology, 1-9. https://doi.org/10.1007/s12144-023-04436-0
Araya, B. M., Aldersey, H. M., Camara, S., Alemu, K., Dyer, S., & Velez, M. P. (2024). The varying estimation of infertility in Ethiopia: the need for a comprehensive definition. BMC Women's Health, 24(1), 280. https://doi.org/10.1186/s12905-024-03118-8
Ashimi, A. O., Aminu, M. B., Adewale, F. B., Abdurrahman, A., & Muhammad, Y. E. (2024). Domestic violence against women with infertility attending gynaecological clinics in Northern Nigeria: A multi-centre study. Journal of West African College of Surgeons, 14(3), 331-338. https://doi.org/10.4103/jwas.jwas_156_23
Braverman, A. M., Davoudian, T., Levin, I. K., Bocage, A., & Wodoslawsky, S. (2024). Depression, anxiety, quality of life, and infertility: A global lens on the last decade of research. Fertility and sterility, 121(3), 379-383. https://doi.org/10.1016/j.fertnstert.2024.01.013
Dadhwal, V., Choudhary, V., Perumal, V., & Bhattacharya, D. (2022). Depression, anxiety, quality of life and coping in women with infertility: A cross‐sectional study from India. International Journal of Gynecology & Obstetrics, 158(3), 671-678. https://doi.org/10.1002/ijgo.14084
DeWolfe, C. E., Galbraith, M. K., Smith, M. M., Watt, M. C., Olthuis, J. V., Sherry, S. B., & Stewart, S. H. (2023). Anxiety sensitivity and physical activity are inversely related: A meta-analytic review. Mental Health and Physical Activity, 25, 100548. https://doi.org/10.1016/j.mhpa.2023.100548
Dong, M., Tao, Y., Wu, S., Kong, L., Zhou, F., & Tan, J. (2022). Changes in sexual behaviour, anxiety symptoms, and quality of couple relationship of patients with infertility during the COVID-19 lockdown. Journal of Assisted Reproduction and Genetics, 39(2), 493-504. https://doi.org/10.1007/s10815-021-02361-4
Eslami, N., Arefi, M., Hosseini, S. A.-S., & Amiri, H. (2022). A comparison of the effectiveness of Emotion-Focused Couple Therapy and Gottman's Cognitive-Systems Couple Therapy on the emotional balance of conflicted couples. Studies of Disability, 12(0), 0-0. https://psychologicalscience.ir/article-1-268-fa.html
Fernandes, J., Pedro, J., Costa, M. E., & Martins, M. V. (2023). Effect of depression and anxiety on sexual functioning in couples trying to conceive with and without an infertility diagnosis. Psychology & Health, 38(1), 58-75. https://doi.org/10.1080/08870446.2021.1955115
Gallagher, M. W., Payne, L. A., White, K. S., Shear, K. M., Woods, S. W., Gorman, J. M., & Barlow, D. H. (2013). Mechanisms of change in cognitive behavioral therapy for panic disorder: The unique effects of self-efficacy and anxiety sensitivity. Behavior Research and Therapy, 51(11), 767-777. https://doi.org/10.1016/j.brat.2013.09.001
Garey, L., Smit, T., Clausen, B. K., Redmond, B. Y., Obasi, E. M., Businelle, M. S., & Zvolensky, M. J. (2024). Anxiety Sensitivity and Distress Tolerance in Relation to Smoking Abstinence Expectancies among Black Individuals Who Smoke. Journal of Studies on Alcohol and Drugs, 85(2), 244-253. https://doi.org/10.15288/jsad.23-00176
Ghafari Cherati, M., Mohammadi Pour, M., & Azizi, A. (2023). The effectiveness of mentalization therapy on emotional regulation difficulties and aggression in depressed adolescent girls. https://psychologyj.tabrizu.ac.ir/article_16935.html
Hassan, H. E., Nasr, E. H., & Mohamed, S. S. A. (2023). Violence against infertile women: a comparative study. Nurse Care Open Access Journal, 9(4), 168-178. https://doi.org/10.15406/ncoaj.2023.09.00279
Jemcov, A., Olthuis, J. V., Watt, M. C., & Stewart, S. H. (2023). Do anxiety sensitivity cognitive concerns and/or depression symptoms independently explain sleep disturbances in a high anxiety sensitive treatment-seeking sample? Journal of anxiety disorders, 97, 102731. https://doi.org/10.1016/j.janxdis.2023.102731
Juul, S., Jakobsen, J. C., Hestbaek, E., Jørgensen, C. K., Olsen, M. H., Rishede, M., & Simonsen, S. (2023). Short-Term versus Long-Term Mentalization-Based Therapy for Borderline Personality Disorder: A Randomized Clinical Trial (MBT-RCT). Psychotherapy and psychosomatics, 92(5), 329-339. https://doi.org/10.1159/000534289
Karbalaei, M., Yazdanbakhsh, K., & Moradi, A. (2024). Investigating the effectiveness of Emotion-Focused Cognitive Behavioral Group Therapy (ECBT) on anxiety and anxiety sensitivity in anxious children. Journal of New Psychological Research, 19(73), 150-159. https://psychologyj.tabrizu.ac.ir/article_17980.html
Khajavand, Z., Bahrinain, S. A., Nasri, Z., & Shahabi Zadeh, R. (2024). A comparison of the effectiveness of Mentalization-Based Therapy (MBT) and Parent-Child Interaction Therapy (PCIT) on emotional regulation and eating behaviors in anxious children. Journal of Psychological Health Research, 19(4), 49-33. https://psychologyj.tabrizu.ac.ir/article_17980.html
Khajeh Hosseini Rabari, F., Rezaei, F., Mirzaei, F., & Sadeghi, F. (2024). The effectiveness of Emotion-Focused Therapy on fear of intimacy, hostile attributions, and emotional dysregulation in women affected by marital infidelity. Psychology Growth, 13(1), 233-242. https://frooyesh.ir/article-1-4874-fa.html
Kremer, F., Ditzen, B., & Wischmann, T. (2023). Effectiveness of psychosocial interventions for infertile women: A systematic review and meta-analysis with a focus on a method-critical evaluation. PLoS One, 18(2), e0282065. https://doi.org/10.1371/journal.pone.0282065
Li, Y. (2023). A cross-sectional analysis of the relationships between anxiety sensitivity and youth irritability: the mediated roles of insomnia and selective attention for threat. BMC psychiatry, 23(1). https://bmcpsychiatry.biomedcentral.com/articles/10.1186/s12888-023-05280-z
Oehlman Forbes, D., Lee, M., & Lakeman, R. (2021). The role of mentalization in child psychotherapy, interpersonal trauma, and recovery: A scoping review. Psychotherapy, 58(1), 50. https://pubmed.ncbi.nlm.nih.gov/32881544/
Olthuis, J. V., Connell, E. M., Watt, M. C., & Stewart, S. H. (2024). What Does 'High Anxiety Sensitivity' Look Like? Using Cluster Analysis to Identify Distinct Profiles of High Anxiety Sensitive Treatment-Seekers. Cognitive therapy and research, 1-13. https://doi.org/10.1007/s10608-024-10476-y
Peel, A. J., Oginni, O., Assary, E., Krebs, G., Lockhart, C., McGregor, T., & Eley, T. C. (2023). A multivariate genetic analysis of anxiety sensitivity, environmental sensitivity and reported life events in adolescents. Journal of Child Psychology and Psychiatry, 64(2), 289-298. https://doi.org/10.1111/jcpp.13725
Richard, Y., Tazi, N., Frydecka, D., Hamid, M. S., & Moustafa, A. A. (2023). A systematic review of neural, cognitive, and clinical studies of anger and aggression. Current Psychology, 42(20), 17174-17186. https://doi.org/10.1007/s12144-022-03143-6
Rousta, P., Bahrinain, S. A., Ahai, G., & Ghani Far, M. (2024). The impact of mentalization therapy on object relations and emotional expression in conflicted mother-child relationships. Journal of Nursing and Midwifery, 22(5), 351-341. https://doi.org/10.61186/unmf.22.5.341
Shokrollahi, M., Hashemi, S. I., Mehrabi Zadeh Honarmand, M., Zargar, Y., & Na'ami, A. (2021). A comparison of the effectiveness of Emotion-Focused Therapy and Analytical Cognitive Therapy on anxiety sensitivity, catastrophizing pain, experiential avoidance, and cognitive emotion regulation in patients with chronic pain and alexithymia. Behavioral Sciences Research, 19(4), 739-752. https://doi.org/10.52547/rbs.19.4.739
Smits, M. L., De Vos, J., Rüfenacht, E., Nijssens, L., Shaverin, L., Nolte, T., & Bateman, A. (2024). Breaking the cycle with trauma-focused mentalization-based treatment: theory and practice of a trauma-focused group intervention. Frontiers in psychology, 15, 1426092. https://doi.org/10.3389/fpsyg.2024.1426092
Soheila, S., Latifi, K., & Zareen, M. (2024). The effectiveness of Mentalization-Based Therapy on psychological status and quality of life in women with hypothyroidism. Journal of Rehabilitation Research in Nursing, 11(3). http://ijrn.ir/article-1-799-fa.html
Taubner, S., Hauschild, S., Kasper, L., Kaess, M., Sobanski, E., Gablonski, T. C., & Volkert, J. (2021). Mentalization-based treatment for adolescents with conduct disorder (MBT-CD): protocol of a feasibility and pilot study. Pilot and Feasibility Studies, 7(1), 139. https://doi.org/10.1186/s40814-021-00876-2
Toope, M., Mirzamani Bafghi, S. M., & Hatami, M. (2025). The Effectiveness of Reality Therapy and Emotion-Focused Therapy on Cognitive Avoidance in Women with Marital Distress. Iranian Journal of Educational Research, 4(2), 0-0. https://ijer.hormozgan.ac.ir/article-1-389-en.pdf
Vanni, G., Selntigia, A., Marsella, V. E., Russo, C., Pellicciaro, M., Materazzo, M., & Exacoustos, C. (2024). Breast Cancer in Patients with Previous Endometriosis Showed Low Aggressive Subtype. Medicina, 60(4), 625. https://doi.org/10.3390/medicina60040625
Warwar, S. (2023). The use of homework in emotion‐focused therapy for depression. Journal of Clinical Psychology, 80(4), 744-761. https://doi.org/10.1002/jclp.23618
Yokota, R., Okuhara, T., Okada, H., Goto, E., Sakakibara, K., & Kiuchi, T. (2022). Association between stigma and anxiety, depression, and psychological distress among Japanese women undergoing infertility treatment.
Zajenkowska, A., Rajchert, J., Macianowicz, O., Holas, P., & Murawic, S. (2019). Cognitive-behavioral (CBT) and psychodynamic (PDT) group psychotherapy and their impact on depressive symptoms and hostile attributions. International Journal of Group Psychotherapy, 69(4), 383-407. https://doi.org/10.1080/00207284.2019.1653189


