Emotional and Cognitive Effects of Long-Term Antipsychotic Medication Use: A Qualitative Study

Abstract

This study aimed to explore the emotional and cognitive effects of long-term antipsychotic medication use. By understanding these impacts, the study seeks to provide a comprehensive view of the lived experiences of individuals who have been on antipsychotic medications for extended periods, highlighting both the benefits and the potential challenges. A qualitative research design was employed using a phenomenological approach to capture in-depth personal experiences. A purposive sampling method recruited 26 participants who had been on antipsychotic medications for at least five years. Data were collected through semi-structured interviews, which were transcribed verbatim and analyzed using thematic analysis to identify common themes and patterns in the participants' experiences. The study achieved theoretical saturation, ensuring that no new themes emerged from the data. The analysis revealed four main themes: emotional impact, cognitive effects, daily functioning, and social interaction. Participants reported significant emotional blunting, including reduced pleasure and emotional responsiveness, alongside cognitive impairments such as memory deficits and diminished attention span. Challenges in daily functioning, such as difficulties in managing routine activities and occupational tasks, were prominent. Social interactions were also affected, with participants experiencing reduced social engagement, dependency on support networks, and stigma related to medication use. These findings are consistent with previous studies, underscoring the profound impact of long-term antipsychotic use on various aspects of life. Long-term use of antipsychotic medications, while essential for managing severe psychiatric conditions, is associated with significant emotional and cognitive side effects that impact patients' quality of life. Healthcare providers should be aware of these effects and engage in regular assessments and open communication with patients to address and mitigate these challenges. Personalized treatment approaches, psychoeducation, and support groups can enhance patients' well-being and treatment adherence.